Micky van de Ven Brace Ends Everton's Run at Brand New Stadium
Micky van de Ven emerged as the first backline player to score twice in a English top-flight game for Spurs since the Belgian defender in March 2013.
Match summary
The Spurs defender heads home two times in first half
Everton's defender has goal ruled after VAR review
Pape Matar Sarr nets third in dying moments
The defeat is the Merseyside club's first at their new ground
Micky van de Ven found the net twice as Spurs extended their unbeaten run in away games in the Premier League and delivered Everton their first defeat at Hill Dickinson Stadium.
The Toffees were undefeated in their last five matches at their recently opened stadium at Bramley-Moore Dock, having left their historic home behind after 133 years at the end of last season.
But Spurs captain Van de Ven struck on two occasions from corners in the opening 45 minutes to place their impressive record at jeopardy, and they were failed to turn it around before the midfielder - set up by ex-Everton forward the Brazilian - headed home a final goal to put the game to bed.
The Everton defender believed he had equalized the tally five minutes after Van de Ven's opener, glancing a powerful header past Guglielmo Vicario from an Everton corner.
Beto, in the meantime, failed to convert a number of chances, while the Italian goalkeeper made a succession of excellent stops to ensure the London club went five matches on the road unbeaten in the English top flight.
But the video assistant referee stepped in, instructing Craig Pawson to review the goal on the screen and the official decided that Jack Grealish and Iliman Ndiaye were in an illegal position and had impeded with the Spurs keeper.
This victory elevates the manager's side into third place in the division, a handful of points off local foes and leaders Arsenal.
Everton remain in 14th position and sit six points ahead of the drop zone.
Tottenham analysis: The defender fulfils duties at each end of pitch
After a drab midweek display in the Champions League against Monaco, where they mustered a only two shots on goal, Frank opted for Randal Kolo Muani in attack instead of ex-Everton forward Richarlison.
The new arrival was failed to make much of an impact before being replaced for Richarlison after 60 minutes on the pitch, but it emerged he wasn't needed in the final outcome.
Defender Van de Ven converted into an offensive threat to be reckoned with.
Spurs' opening strike came from a well-worked corner routine, with the midfielder directing the ball toward the six-yard box for an free Van de Ven to score.
And Ven de Ven - stepping up as captain in Cristian Romero's absence - added his next goal in first-half stoppage time as he outjumped Jordan Pickford to head home.
The Dutchman was just as impressive in defence, partnering effectively with his defensive colleague as the duo dealt superbly with the numerous deliveries sent their way by Everton.
Everton analysis: Toffees missing finishing touch
Everton's new home had been a fortress, but it appears the freshness may have faded somewhat and supporters headed to the gates after Sarr's final goal for Spurs.
The break in Everton's unbeaten home run won't be a major worry for David Moyes, but their attacking woes will be.
Beto and the other striker - the Toffees' pair of recognised centre-forwards - had netted just one league goal between them before Sunday's match.
And they were failed to contribute to that poor tally on a wet and gloomy night on Merseyside.
The striker's performance was summed up when he chose to overhead kick a golden opportunity from near the goal, despite having room and time to reposition for a simpler attempt that would have tested the keeper.
Barry, as well, failed to influence the game after replacing the starter in the 65th minute.
It wasn't for a shortage of chance. Most of the home side's attacks came through Grealish and the forward, who relentlessly delivered dangerous balls into the Tottenham box.
Upcoming fixtures for these two sides?
The Toffees: The team head to Sunderland in the Premier League on early November at 20:00 GMT.
Tottenham: Spurs go to St James' Park on Wednesday, 29 October for their fourth-round League Cup tie against Newcastle.